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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1416 | Ayanin | IL Receptor , P450 , PARP , PDE | |
Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio... | |||
T5424 | Etosalamide | Ethosalamide | Others |
Etosalamide (Ethosalamide) is an antipyretic and analgesics agent. | |||
T5310 | TR-14035 | MDK-1191 | Integrin |
TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM). | |||
T0059 | Diphenylpyraline hydrochloride | 4-Diphenylmethoxy-1-methylpiperidine hydrochloride | Histamine Receptor |
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re... | |||
T21060L | NPC 567 acetate | NPC 567 acetate(109333-26-8 Free base) | Bradykinin Receptor |
NPC 567 acetate is a bradykinin B2 antagonist and can be used in studies about the treatment of allergic airway disease. | |||
T72031 | BI 1015550 | PDE | |
BI 1015550 is an orally active inhibitor of PDE4B with an IC 50 value of 7.2 nM. BI 1015550 has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmo... | |||
T3S1612 | Kuwanon G | Moracenin B,Kuwanone G | Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase |
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a... | |||
T70333 | PM-43I | ||
PM-43I is a potent inhibitor of both STAT5- and STAT6-dependent allergic airway disease in mice. | |||
T13263 | COX/5-LO-IN-1 | Atreleuton analog | COX |
COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states. | |||
T31072 | CP-664511 | UNII-W1AEF8025F,CP664511 | |
CP-664511 is an alpha4beta1/ vascular cell adhesion molecule-1 (VCAM-1) inhibitor with therapeutic potential for allergic airway disease. | |||
T16476 | PF-03654746 | Histamine Receptor | |
PF-03654746 is a selective antagonist of the histamine H3 receptor. PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimer's disease. PF-03654746 can be used in studies about the treatment of ... | |||
T60864 | Sequifenadine | ||
Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2]. | |||
T74646 | PM-81I | ||
PM-81I, a potent STAT6 inhibitor targeting the SH2 structural domain, effectively reduces STAT6 phosphorylation levels. It is applicable in the research of allergic lung disease, allergic rhinitis, chronic obstructive pu... | |||
T73129 | STAT6-IN-1 | ||
STAT6-IN-1, a STAT6 inhibitor, exhibits high affinity for the SH2 domain of STAT6 (IC 50 = 0.028 µM), making it suitable for research on allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease, or... | |||
T68280 | Adriforant | ||
Adriforant, also known as ZPL-3893787, PF-3893787 and ZPL-389, is a novel histamine H4 receptor antagonist. Adriforant shows an excellent in vitro profile that warrants their further investigation in relevant models of ... | |||
T26628 | Andolast | CR2039,CR-2039,CR 2039 | |
Andolast, also known as CR-2039, an anti-allergic agent for the treatment of bronchial asthma, chronic obstructive pulmonary disease (COPD). Andolast acts at different cellular levels to inhibit immunoglobulin E synthesi... | |||
T75499 | Maceneolignan H | ||
Maceneolignan H (Compound 8), a neolignane derived from the arils of Myristica fragrans, acts as a selective CCR3 antagonist with an EC 50 value of 1.4 μM. This compound shows promise for allergic disease research [1]. | |||
T69918 | Adriforant tartrate hydrate | ||
Adriforant tartrate hydrate, also known as ZPL-3893787 tartrate hydrate, PF-3893787 tartrate hydrate and ZPL-389 tartrate hydrate, is a novel histamine H4 receptor antagonist. Adriforant tartrate hydrate shows an excelle... | |||
TN2511 | Britannilactone diacetate | 1,6-O,O-Diacetylbritannilactone | IL Receptor , PARP , ROS , MAPK , Caspase , JAK , JNK , STAT |
1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic acti... | |||
T71329 | Theophylline-d6 | ||
Theophylline-d6 is intended for use as an internal standard for the quantification of theophylline by GC- or LC-MS. Theophylline is an inhibitor of phosphodiesterase. It is also an adenosine A1 and A2 receptor antagonist... |